Sentence examples for considerable binding affinity from inspiring English sources

The receptor 1 is found to have considerable binding affinity for weakly basic anions even in polar solvent such as DMSO.

Compounds from this series exhibited considerable binding affinity (Ki = 1 nM) and functional activity at MCH-R1, acceptable CYP2D6 inhibition, and good rat brain exposure.

However in the absence of endogenous Bub1 considerable binding affinity is regained.

(B ) Representative images of HeLa cells transfected with the indicated GFP-Bub1209 409 GFP-Bub1209 409wing that this constructs which lackshowing-thatinal thisdomain, does not regain constructble binding affinity in the absence of Bub1.

These two compounds displayed extra precision docking scores of -7.972908 and -7.575686 respectively suggesting considerable binding affinity for cathepsin L. High activity values of 5.72 and 5.75 predicted using the 3D QSAR model further substantiated the inhibitory potential of these identified leads.

And two of the designed aminoacyl-tRNA synthetases had considerable binding affinities.

Among 60 mutated aminoacyl-tRNA synthetases, 15 of them showed binding ability to p-acetyl-L-phenylalanine, of which two had considerable binding affinities.

A considerable enhance in the binding affinity was observed, when compared with the zwitterionic PC, with a Kd of 0.04 µM.

Alanine scanning mutagenesis of the ID have indicated that residues Thr704, Phe705, Glu706, Tyr708, Leu709, His710, Asn711 and Phe714 display a considerable loss in insulin binding affinity upon mutation [31].

There is considerable variation in the binding affinity of ER-α and ER-β among different estrogens (Kuiper et al. 1998).

Antibacterial activities and DNA binding affinity of this class of cadmium complexes have attracted considerable interest.