Sentence examples for considerable alterations to from inspiring English sources
The heterogeneity of alveolar microstructure that is accounted for in image-based models resulted in considerable alterations to the shape of the 129Xe diffusive uptake curve when compared to 1D models.
Cases with previous surgical treatment were also excluded because considerable alterations to the venous drainage would be present due to the first operation.
Unstable clastic grains like feldspars suffered considerable alteration to kaolinite when exposed to meteoric water of low ionic strength near the surface.
Strong increase of hole mobility and decrease of hole concentration have been observed in CrSi2 epitaxial films on Si(111) [3] that corresponds to considerable alterations in their band structure.
From the above discussion, it appears convincing that the CNS drugs can serve as suitable leads for non-CNS targets after appropriate structural modifications leading to considerable alterations in their property space.
Given the functions of miRNAs in post-transcriptional gene silencing, loss of Dicer and all microRNAs would be expected to result in considerable alterations in mRNA levels and associated phenotypic changes.
Besides, miRNA-target interactions that are involved in the repression of protein synthesis may not result in considerable alterations in the transcript expression level, hence leading to uncorrelated expression profiles.
Interestingly, in contrast with R6/2 and some of the knock-in mice where there are considerable alterations in receptor expression, alterations in YAC128 mice appear limited to glutamate receptors, as DA, GABA (γ-aminobutyric acid) and adenosine receptor binding remained unchanged (Benn et al., 2007).
The Borana rangelands have undergone considerable alterations between 1987 and 2003.
However, we did not find any considerable alterations in HAT activity with SFN treatment in these breast cells (Fig 5C).
Considerable alterations in the DNA binding activity of SRF upon serum induction are either not observed or are associated with additional events such as phosphorylation, depending on the cell type, the stimulus and the target gene [22], [23], [24], [25].
