Sentence examples for considerable alterations of from inspiring English sources

We conclude that during MCTS formation considerable alterations of various cellular molecules occur.

Interestingly, it seems that even early mutants such as RutC-30 bear considerable alterations of their genome (Seidl et al. 2008).

Hypertrophic growth of PNx kidneys is accompanied by considerable alterations of the metabolic state of the remaining nephrons (called also hypermetabolism of the remnant kidney) manifested by an increased net glucose production [ 30], accumulation of inorganic phosphate [ 28], and inefficient oxygen utilization per nephron and per sodium transport [ 27- 29].

Since MMP-7 is involved in a variety of cellular mechanisms, including processing of inactive precursor proteins, ectodomain shedding of extracellular signaling molecules and remodeling of the extracellular matrix (ECM), respectively, we could observe considerable alterations of the ECM during senescence of HMEC.

Some believe it is preferable to perform an IOL exchange rather than a new fixation of the same IOL, particularly in cases of traumatically dislocated iris-claw IOLs, because of the considerable alterations on the affected haptics of the IOLs, which might not guarantee a reliable re-enclavation.

Surprisingly, addition of organoclay to the blends promoted a drastic increase in the notched Izod impact strength and a considerable alteration of the shape of the dispersed EVA phase when the organoclay is located in this phase.

Opencast coal mining activities trigger considerable alteration of soil structure, and characterizing the spatial variability of soil particle size distribution (PSD) quantitatively can contribute to understand mined soil properties and perform mined land rehabilitation.

If confirmed by future studies, loss of Shank in placozoans would imply disruption or at least considerable alteration of the macromolecular architecture of the PSD-like protein complex.

Our results show considerable alteration of femoral antetorsion with variation of FT, even when the same rotational alignment at the proximal part of the femur (iAT) is applied.

At that time point, we found a considerable alteration of the expression of genes encoding transcription factors that could set off new signal pathways that allow the correction of the destructive processes that developed after vascular occlusion.

The heterogeneity of alveolar microstructure that is accounted for in image-based models resulted in considerable alterations to the shape of the 129Xe diffusive uptake curve when compared to 1D models.