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When deciding to use a generic instrument or a disease (condition) specific instrument to measure HRQL, it is important to consider the responsiveness of a HRQL instrument [ 37].
The FDA (2000) recommended that new drug applicants consider "the responsiveness of particular organs and tissues" in addition to general sensitivity when selecting rodent species, strains, and substrains for testing.
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In considering the responsiveness of taxpayers in this category, the HMRC has a range of possible estimates.
We also considered the responsiveness of cells lines in the context of known downstream signalling pathways.
To our knowledge, none of the studies that have considered the responsiveness of HRQoL instruments in community-based stroke patient field have estimated MIDs.
In this section, we propose a novel QoS model to consider both the responsiveness in serving user mapping requests and the quality of returning geographic information.
Thus, considering the poor responsiveness of NSCLC cells to conventional therapy, alternative pathways that trigger cell death might be beneficial for efficient killing of these tumors.
When evaluating an activist campaign, many investors consider the company's record of responsiveness to their concerns and will be less inclined to actively support a company that has ignored requests for dialogue.
With product-responsiveness, we encourage to consider the option of 'open-ended products' in operationalising responsiveness to diverse societal needs.
Thus, while the available measures were considered appropriate, the responsiveness and known groups analysis for example may have been improved with the inclusion of a patient global impression of concept item.
When considering evidence of responsiveness, it is important to consider the extent to which these factors affect reported estimates of responsiveness [ 9].
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