Interestingly, the mouse gene B4galnt2 (encoding glycosyltransferase β-1,4-N-acetylgalactosaminyltransferase 2) has similar function in terms of determining the sugar composition of the intestinal mucosa, and it is tissue-specific when we consider the expression patterns.
However, most similarity measurement techniques including Pearson correlation usually consider the expression patterns between two genes under the same conditions or at the same time points, no time-lagging analysis is taken into account.
These results supported, at least partly our findings that nuclear expression of HO-1 might be essentially correlated with the malignancy of CRC, and strongly suggested that it is critically important to consider the expression pattern of HO-1 in tumor cells when evaluating the roles of HO-1 in tumors.
In the first iteration, we examined the hypergeometric enrichment obtained when considering the expression patterns of the targets of only the first miR-seed.
In the second iteration, we examined the hypergeometric enrichment obtained when considering the expression patterns of the targets of the first and second miR-seeds, and so on.
Finally, cluster 1 included many homologs of A. thaliana SPL genes (SPL2, SPL3, SPL4, SPL5, SPL8 and SPL9) what will be discussed later when considering the expression patterns observed within this gene family.
Considering the expression patterns of both transcription factors and mature-related genes, we infer that less rainfall and stronger sunshine in the GT region could initiate the earlier expression of ripening-related genes and accelerate the berry maturation, eventually limiting the production of terpene volatiles.
Finally, we considered the expression pattern of Wnt1, which is the same in both steady states.
Considering the expression pattern of ND chondrocytes, hierarchical clustering resulted in two main groups, classified as ML and scaffold.
Considering both the expression patterns of each clade and the events of gene duplication that generated them, it seems likely that after the first gene duplication, the ancestor of genes in clades 3 and 4 produced the differences between inner (expression "on") and outer tepals (expression "off").
Previous studies did not consider the different expression patterns throughout the tumours (diffuse versus perinecrotic) that have been shown in other cancers to be prognostically crucial[ 7].
