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Both of these measures consider specificity on a continuum, i.e. do not discretely separate parasites into specialists (single host) and generalists (two hosts and more).
When selecting scales to measure outcome parameters, we did not only consider specificity and reliability of instruments but also practicability.
Second, predictive genetic associations must also consider specificity and sensitivity analyses to confirm that genotypic information contributes to predictions of response to therapy or outcome beyond what is possible using classical measures (age, severity of illness, and so on).
Finally, we should consider specificity in computing similarities, since both distributions of compound connectivity and enzyme EC number hierarchy show large variation [ 9, 18], i.e. some compounds and EC subclasses appear more often than the others in the background.
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Considering specificity and sensitivity of categorization we found that lowest average amount of remaining target RNA is achieved in the ΔG range from −10 to 0 kcal/mol.
For this reason we only considered specificity and PPV as important values.
We have also compared the performance of all the matrices considering specificity as proportion of true hits among all positive predictions using ROC curve.
Moreover, considering specificity of compounds may result in more biologically meaningful pathways, since metabolic pathways seem to represent paths through the least "promiscuous" compounds [ 18].
When considering specificity and PPV (i.e. the false-positive rate) as the most important criteria for evaluating new approaches for analysing microarrays that partially lack reference signals, a definition of sequence presence based on a signal higher at least twice as high as the background and higher than the reference signal (method 4) showed the best test characteristics.
When considering specificity and PPV (i.e. the false-positive rate) as the most important criteria for evaluating these methods, the method that defined gene presence based on a signal at least twice as high as the background and higher than the reference signal (method 4) had the best test characteristics.
Given that treatment side effects negatively impact every level of HRQOL, we recommend a better medical follow-up of side effects, considering specificities related to gender.
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CEO of Professional Science Editing for Scientists @ prosciediting.com