After identifying upregulated genes of the whole community we selected those upregulated genes corresponding to the red complex (Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia ), which are consider major periodontal pathogens.
After identifying downregulated genes of the whole community we selected those downregulated genes corresponding to the red complex (Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia ), which are consider major periodontal pathogens.
If a dyed-in-the-wool Zone 5 gardener can toss away her forcing forsythia, picking up her roots and replanting them in the land of the bougainvillea, then surely the garden club can consider me again.
A triad of the so-called 'red complex', a group of three oral anaerobic bacteria, Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia, has traditionally been considered to cause periodontitis.
Considering the lack of reliable fossil record in genus Forsythia, the average divergence time was estimated via calibrating molecular clock implemented in MEGA 5.2 [ 51].
In addition, the microorganisms which are usually considered as pathogens of periodontitis, P. gingivalis, T. denticola and T. forsythia, are not the sole representatives of the periodontitis microbial signature.
The red complex, which appears later in biofilm development, comprises three species that are considered to be the major periodontal pathogens: Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia [ 7, 8].
In fact, although this species is considered a recognized periodontal pathogen associated with human subgingival biofilm in periodontal pockets, other studies assessing the ligature-induced biofilm in rats also did not find T. forsythia among the bacteria population [ 47].
The study describes two novel glycolipids in T. forsythia which could be essential in this organism.
Its official name is Thomas Moran's Forsythia, even though we didn't see a single forsythia, real or painted, anywhere on the premises.
