Exact(7)
Moreover, it is possible to consider duplication in series of production stages, which is an alternative that has not been used till now.
We do not consider duplication and divergence of genes.
Author response: I consider "duplication" to be included under the notion of "rearrangement".
Here, we consider duplication and loss of proteins, loss and formation of interactions, and adjustment of kinetic rates as such processes (see Methods).
b) We are tempted to consider duplication as a primary driving force in the adaptive evolution of genomes, but this "master" mutation still has to be integrated into an evolutionary context to assess its importance in genome evolution.
However, duplication and transfer events frequently occur together, particularly in prokaryotes, and the analysis of such families requires reconciliation methods that can simultaneously consider duplication, transfer and loss events.
Similar(53)
We can calculate the steady-state distribution of edges per node (mean degree ⟨ k⟩) by calculating the total number of nodes n and edges m as a function of the number of events N and the parameters P N, P E, p, and q (we do not consider duplications in this calculation).
Ohno (1970), in particular, considered duplication and divergence of genes a critical requirement for major evolutionary diversification: "Natural selection merely modified while redundancy created," he wrote.
Other members of the GH family were considered duplication products of this gene [9].
For this purpose, we only considered duplication events showing a consistency score (58) of >0.3.
For this purpose, we only considered duplication events showing a consistency score above 0.3 (Vilella et al., 2009).
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