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10 As for bone density, estrogens typically reduce bone resorption, thereby conserving bone mass.
Approximately 20% of bone mass is genetically determined; however, the risk of osteoporosis can be reduced by optimizing bone mass increasing during youth, conserving bone mass during adulthood, and minimizing bone mass loss during advancing age [ 5- 7].
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11 In other words, estrogens conserve bone mass, while testosterone may increase bone mass.
The Mayo design conserves bone mass, while simultaneously reducing the incidence of stress-shielding compared to the Alloclassic, revealing a key benefit of the distinctive geometry.
These medications suppress bone resorption, maintain bone mass, and prevent bone fractures.
Weight-bearing exercise can increase peak bone mass in teenagers and help maintain bone mass in post-menopausal women.
Bisphosphonates work by inhibiting that breakdown, thereby conserving bone density.
These findings demonstrate that inhibitors of COX-2 and sPLA2-IIa can effectively suppress OVX-induced bone loss in the adult rat by conserving trabecular bone mass and architecture through reduced bone remodeling and decreased resorptive activity.
We hypothesized that the conserved C-terminal MEPE ASARM-motif is chiefly responsible for regulating bone mass and trabecular structure.
In conclusion, these data identifies NPY as a critical integrator of bone homeostatic signals; increasing bone mass during times of obesity when hypothalamic NPY expression levels are low and reducing bone formation to conserve energy under 'starving' conditions, when hypothalamic NPY expression levels are high.
Bone mineral density, estimate of bone mass.
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