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In contrast, the orthologous pair of Os04g51320 and Sb06g027540, conserved the expression pattern in response to cold, drought, and salt (Fig. 4).
Intuitively, one might assume that the distance between two orthologous genes which have conserved the expression profile of their last common ancestor should be close to zero, and that this should hold regardless of the gene expression pattern.
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TPK3 is repressed in those species, conserving the expression pattern of its ortholog in all the respiratory pre-duplication species (data not shown).
According to this loss of expression model, boule has evolved by selective loss of expression, whereas dazl has conserved the original expression.
These functions of FOXO in the insulin signaling pathway and the response to ROS, and its role in promoting longevity, appear to be evolutionarily conserved: When the expression level of FOXO is perturbed, the corresponding changes in gene expression patterns as well as the resulting phenotypes are similar across distantly related species (reviewed by [26]).
Underlying the variability in the roles and morphogenesis of the notochord across the chordates is a core conserved feature: the expression of the gene brachyury (bra) and its apparent involvement in notochord specification throughout the phylum [ 2].
Theory concerning the evolution of dosage compensation predicts that stabilizing selection to conserve the ancestral expression ratios between autosomes and the nascent sex chromosomes should produce a global pattern of equal M F sex ratios on the sex chromosomes.
The comparisons between all three species show that even though fewer tags are conserved over this evolutionary distance, when they are conserved in sequence, the expression levels are conserved as well.
The conserved notochord expression of Brachyury homologs in Ciona and Oikopleura prompted us to use the 50 notochord genes identified so far as bona fide Ciona Brachyury (Ci-Bra) targets to assess whether, and to what extent, Oikopleura retains the notochord gene battery identified in Ciona.
The conserved gene expression profiles in tissue comparisons among species have provide a solid basis for comparative genomics study.
This expression instead appears to be an artifact attributed in part to the conserved, overlapping expression profiles of Moocci.Tbx6-r.b and Moocci.Lhx3/4.b, even if this overlap is not instructive for endogenous Moocci.Mesp activation.
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