Sentence examples for conserved surfaces from inspiring English sources
Conserved surfaces are formed by the phosphotyrosine recognition loop (KNRY motif) and by conserved glutamine residues of the Q loop.
In one crystal form, stomatin assembles via two conserved surfaces into a cylindrical oligomer, and these oligomerization surfaces are also essential for the inhibition of ASIC3-mediated currents.
We have shown that the SD2 domain from Drosophila Shroom forms a three-segmented anti-parallel coiled-coil dimer with highly conserved surfaces that mediate Shroom-Rock interactions.
To further test the contribution of the last few TPRs and TLRs, we mutated residues on the conserved surfaces close to the active site and studied differences in self-glycosylation and activity towards TAB1.
To elucidate the architecture of a eukaryotic exosome, its conserved surfaces, and the structural basis for RNA decay, we report the X-ray structure determination for the 286 kDa nine-subunit human exosome at 3.35 Å.
Furthermore, the conserved surfaces also correspond to the regions involved in monomer-monomer interactions.
A plot of the surface of CifPl coloured according to sequence conservation across the protein family reveals conserved, surface accessible residues cluster in two locations (Fig. 4(a)).
The functional diversity appears as different conserved surface patches throughout this common fold.
We have also localized the site of guanine nucleotide exchange activity to a highly conserved surface encompassing several subunits.
The Notch3 NRR uses a highly conserved surface on the third LNR module to form a dimer in the crystal.
The GapC protein is highly conserved surface dehydrogenase among Streptococcus dysgalactiae (S. dysgalactiae) and is shown to be involved in bacterial virulence.
