Sentence examples for conserved surface from inspiring English sources

A plot of the surface of CifPl coloured according to sequence conservation across the protein family reveals conserved, surface accessible residues cluster in two locations (Fig. 4(a)).

The functional diversity appears as different conserved surface patches throughout this common fold.

The Notch3 NRR uses a highly conserved surface on the third LNR module to form a dimer in the crystal.

We have also localized the site of guanine nucleotide exchange activity to a highly conserved surface encompassing several subunits.

Structure-based mutagenesis identified a highly conserved surface centered around blade five that is required for the physical interaction between Prp19 and Cwc2, another essential splicing factor.

The GapC protein is highly conserved surface dehydrogenase among Streptococcus dysgalactiae (S. dysgalactiae) and is shown to be involved in bacterial virulence.

Further site-directed mutagenesis and functional complementation identified 14 highly conserved surface-exposed residues, as well as additional residues involved in TraC dimerization [186].

In order to further characterize this interaction, three Rpn12 mutants were constructed by changing conserved surface-exposed residues to alanine.

Substituting highly conserved surface-exposed capsid tyrosine residues for phenylalanine residues results in increased infectivities for several AAV vectors [ 21– 27].

Interestingly, the conserved surface-exposed Arg97 at interface-2, is at an identical position to a mutant allele u64 of mec-2 that produces some touch insensitivity in worms (Chalfie and Sulston, 1981).

In summary, 4CMenB is a multi-component vaccine containing three broadly conserved surface-expressed recombinant antigens and a specific OMV, thereby providing broad protection against circulating heterologous strains of MenB.