Sentence examples for conserved substitution from inspiring English sources

Despite this striking reversal in polarity, the predicted nra protein products of Alab49 and the M49 strain differ at only a single amino acid residue, via an Asn-Lys conserved substitution.

To determine the role of each residue of AChE586-599 in the process of amyloid formation, a library of alanine scanning mutants along with a structurally conserved substitution mutant (Tyr to Phe) and a truncation mutant (missing the last residue) were used.

While in almost all plant TIPs both NPA motifs are strictly conserved, substitution in NPA motif of loop B is observed in 21 out of 25 SIP members.

Comparisons across 12 Drosophila species for individual genes subject to stop codon readthrough revealed that 97% of readthrough codons were perfectly conserved; substitution of an alternative stop codon was rare and involved only UAA and UAG (Jungreis et al. 2011).

A less discussed issue, however, is that 3-ketosteroid receptors present also a subclass conserved substitution at residue 188 of the D-box, from the usual glutamine recovered in this study at the set 3 of the correlation network to a proline residue.

This feature is not conferred by the evolutionarily conserved substitution of alanine 66 for proline (Figure 4).

Consensus line: asterisks indicated identical residues; colons indicated conserved substitutions; and periods indicated semi-conserved substitutions.

Furthermore, the tripeptide that comprises the putative 50s loop of ISP1 (HQT) has no conservation with ecotin (LHR), whereas ISP2 (VYR) bears conserved substitutions in those positions.

Ten residues are identical to the horseshoe crab tachylectin-2 sequence, while 3 are conserved substitutions (M23L, I70L and V76I), and 3 are semi-conserved (D18A, N31T and D65G).

These desirable properties have been attributed to highly conserved substitutions of the hydrophobic residues of VH domains, which normally interact with complementary VL domains.

It is of particular interest that in all cases in which 4E10 resistance was associated with a substitution at position 680, highly conserved substitutions elsewhere in the MPER were also present.