Sentence examples for conserved shape from inspiring English sources

Thus, substrate specificity should be based on a conserved shape rather than a particular amino acid sequence.

For CpG poor promoters, we observed a profound loss of DNA methylation at the TSS and the surrounding regions, however with conserved shape of the overall structure (Fig. 1G and H).

The fact that most DMPs appear to have large mean total counts may partly be due to the fact that most changes appear at promoters that are strongly enriched in H3K4me3 under normal conditions [ 24], and partly because the peaks with low total counts are more dominated by noise and do not exhibit a conserved shape between WT and Resc.

However, although this one of the oldest arachnid is highly conserved in shape all along, they occupy vast territory of the world from Africa to Asia, Australia and America.

We combine crystal structures of CIDRα1 EPCR complexes with analysis of 885 CIDRα1 sequences, showing that the EPCR-binding surfaces of CIDRα1 domains are conserved in shape and bonding potential, despite dramatic sequence diversity.

show that EPCR-binding surfaces of PfEMP1 are conserved in shape and bonding potential, despite sequence diversity, and identify features that should be mimicked in immunogens preventing EPCR binding.

The technique is able to conserve the shape of arbitrarily shaped rigid bodies and predict terminal velocities of rigid spheres.

HIFU therapy, in combination with other therapies, has the potential to improve both oncologic and cosmetic outcomes for breast cancer patients by providing a curative therapy that conserves mammary shape.

Pair-wise structural comparisons revealed that 19/22 pairs with >55% overall sequence identity had active site Cα RMSD <1 Å, >85% side chain identity, and ≥80% PSAPF (similarity based on pharmacophoric properties) indicating highly conserved active site shape and chemistry.

While the enzymatic activity and polymerization capacity of CtpS is universally conserved, its cell shape function appears to be species specific.

For each of two test geometries undergoing volume-conserved shape changes, the transition state model predicts the same trajectories for detachment/attachment-limited transport as does a continuum model based on the crystalline formulation (Carter et al., Acta metall. mater., 1995, 43, 4309).