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The fully-discrete formulation inherits the main characteristics of conserved phase dynamics, namely, mass conservation and nonlinear stability with respect to the free energy.
Thus it could be easily imagined that both sides of the conserved phase 1 intron insertion site could be confronted by the high evolutional conservative pressure or strict parallel evolution to be adaptable for binding to the partner proteins.
Both conserved positions in the amino acid sequence of the protein and conserved phase and positions of introns are instrumental for this search.
All of the nine full length genes in X. tropicalis contain a second CDS intron (phase 0) in addition to the completely conserved phase 2 intron.
The last domain of nasonin-2 has high sequence identity (86%) and a conserved phase 1 intron after signal peptide to nasonin-1, suggesting it originated from one ancestral copy of nasonin-1 by exon duplication and subsequent intron loss.
A conserved phase 0 intron located at a nearly identical position among all these peptides supports their evolutionary relatedness.
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These findings provide explanation for the conserved phased loop-to-base processing of MIR159/319 genes as framework for post-transcriptionally regulated expressions of their mature miRNAs.
Such an alternative 5' splice site can be also predicted in C. savignyi, with the two alternative introns conserving phase 1 and canonical consensus splicing sites as in C. intestinalis.
The derivation applies to any numerical algorithm which conserves phase-space volume.
Adolescence is an evolutionarily conserved developmental phase characterized by hormonal, physiological, neural and behavioral alterations evident widely across mammalian species.
Because of the non-Hamiltonian nature of the dynamics, the Liouville theorem does not apply, which means that elementary volume elements are not conserved in phase space.
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