In contrast, the sequences of eutherian specific microRNAs that are not related to any known retrotransposon are in most cases conserved almost perfectly among different eutherian species.
According to miRBase [ 29], an authoritative miRNA database, miR-26a belongs to one of the miRNA families broadly conserved with perfectly identical sequences among vertebrates.
Of general interest is the small cohort of protein domains that remain perfectly or nearly perfectly conserved across all seven organisms, represented by the alignments in the 91-100% range.
We show that CLE and CLEL genes are found in the Pinophyta with gene numbers and sequence diversity similar to angiosperms, yet their active peptide sequences are not perfectly conserved, with one exception, the conserved CLE41/44-TDIF CLE41/44-TDIF
In an alignment of all EpsH homologs, we found only six perfectly conserved residues, in three motifs with two conserved residues apiece.
Genomes of 7653R and MAFF303099 were found to share a large set of orthologs and, most importantly, a conserved chromosomal backbone and even larger perfectly conserved synteny blocks.
These two strains share a large set of orthologs and, most importantly, a conserved chromosomal backbone and even larger perfectly conserved synteny blocks.
Recent studies have identified long, non-coding genomic regions that are perfectly conserved between human and mouse, termed ultra-conserved regions (UCRs).
Firstly, the four uORF C-terminal amino acids that are excluded in the fusion EST are perfectly conserved in monocot and dicot members, and the position of their stop codon is perfectly conserved, therefore it is difficult to explain this conservation if the uORF is not translated.
Concerning the conservation of the cluster, it was found to be almost perfectly conserved in C. glutamicum and C. efficiens (Fig. 2), as well as in the recently sequenced C. jeikeium [ 21].
Moreover, the conformations of the residues at the dimer interface were perfectly conserved.
