Sentence examples for conserved orientation from inspiring English sources
In annotating predicted loci as sharing conserved synteny with known ncRNA-encoding loci, homology and conserved orientation relative to EITHER the nearest upstream OR nearest downstream gene of the previously identified locus was regarded as sufficient.
(ii) The conserved orientation of the blocks relative to the centromeres [ 1] indicates that they were formed from larger duplicated blocks (i.e. duplicated whole chromosomes) by reciprocal translocation.
We applied a computational approach (FrameWoker software, release 5.4.3.3) that has been shown to identify conserved orientation, relative position and relative distance of binding motif (matrix) clusters [ 34, 35] also known as the "motif grammar" [ 36] using the Matrix Family Library Version 7.1.
In the Kin1 reconstructions as with Kin3 helix-α4 forms a major contact at the tubulin intradimer interface and adopts a conserved orientation relative to the MT. However, the C-terminus of the Kin1 helix-α4 is shorter by one turn compared to Kin3 because its loop12 is shorter and also lacks the lysine cluster characteristic of Kin3s (compare e.g. Figure 4B,D).
Nadeau and Taylor gave a list of features viewed as supporting inclusion of markers in an SB, a list that includes conserved orientation, conserved adjacency and conserved position of homologous markers associated with the corresponding mapped chromosomes, a collection of features that loosely defines what is more commonly called today collinearity.
As can be seen in Figure 2C, 77% of the 2HOM blocks in P. infestans have a conserved gene orientation (pink triangle), whereas the conserved orientation in the reshuffled genomes is much smaller (blue line).
This study illustrates a case where the naturally conserved 180° orientation of the ori and ter sites has been modified by a large chromosomal inversion in a strain of B. anthracis, CDC 684.
It searches for scaffolds with bonds that are geometrically similar to the defined query bonds and that therefore can conserve the orientation of the query substituents.
For Type 1 orientation, conserved NOLP cases would be able to overlap conserved promoter elements for the complementary gene; this is investigated below through analysis of positions of CHIP-seq peaks.
Orthologous segments (OS) are defined as genome segments derived from a common ancestor without large rearrangements, therefore containing genes showing homology, collinearity, conserved order and orientation in different species [ 52, 53] (Additional file 3).
