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These findings suggest a highly conserved organization of FRS operators.
In order to see whether this conserved organization reflects a functional link between these genes, we tried to determine whether they were transcriptionally linked.
Some of these genes are in regions which showed conserved organization with the GR physical map contigs.
Over 75% of these 1252 links presented a highly conserved organization between the seven Pea LGs, and the eight M. truncatula pseudo-chromosomes (Additional file 14: Figure S8).
Comparative cross-species analysis of the gene order indicates a highly conserved organization across the human-bovine breakpoints within the interval from FGBP1-QDPR-LAP3 to DMP1-IBSP-SPP1-PKD2 on HSA4, MMU5, and RNO14.
For Ficedula albicollis, 73% of the genome sequence was assigned to chromosomes using the flycatcher linkage map; by comparing conserved organization with zebra finch, a total of 89% could be assigned [ 6].
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This is the case of the SEED (4) and IMG (5) resources which offer the visualization of conserved synteny results (i.e. gene clusters that share locally conserved chromosomal organization).
The CCN proteins share a strikingly conserved multimodular organization with distinctive functional features [ 1].
Each Daphnia ortholog contains conserved intron/exon organization typical of their respective insect orthologs.
Interestingly, known insect-specific antisense transcribed miRNAs mir-307 and iab-4 do not exhibit conserved genomic organization in A. gambiae.
However, even without additional data, contig order can be predicted by comparison with a reference genome that is expected to have conserved genome organization.
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