Since our focus is on motif conservation among proteins derived from different genes, we conserved only one record per gene to eliminate the bias that would be introduced by genes with high number of redundant splice variants.
We found that 16S rRNA genes of B. anthracis were highly conserved; only one 16S type (16S type 6) was identified in all 86 strains tested.
Germany is renowned for its astute attacking ability but few would consider the fact that it has conserved only one clean sheet in its past nine fixtures – which came against the Faroe Islands – and it has now conceded six goals against opponents like Austria, Ireland and Sweden.
In contrast to the lineage-specific phenotypic changes, the HCNSs which are conserved only in one particular lineage have not been well studied.
In contrast there are a large number of genes that appear specific to individual Plasmodium species and conserved only in one or two others.
Further investigating the retinal binding pocket at approximately 10 Å (where 1 Å=0.1 nm), we identified two unique residues that were not conserved only in HwHR; one was Thr and the other was Ser of HwHR.
Further, regions which are found to be conserved only between species in one paralogue type may be important for differential regulatory control between the paralogues, while differences between species within a single paralogue type may help identify regions not important to regulation.
The first permutation preserved both the rank and the spacing between the pTU and we only modified the location of the singletons; the second one conserved only the rank of the pTU and we modified the number of singletons between them; the third permutation changed both the rank and the location of the pTU; and, finally, in the fourth one all the genes were randomly distributed.
Except one miRNA that is conserved only in primates (hsa-miR-198, Table 1), we required the miRNA target sites to be conserved in mammals.
If so, then this mode of regulation is poorly conserved over evolutionary time, because transcriptional overlap is conserved for only one gene pair across E. cuniculi, A. locustae, and T. hominis [ 40]: ribosomal protein L6 (THOM_0162) and RNA polymerase III transcription factor IIIC subunit 5 (THOM_0163), which overlap in the 3′ UTR.
7C, D), S3, K5, I6, R9, L10, N36 seems to be well conserved, since only one residue, I6, was found to be variable (italic), and the rest exhibit an average index of conservation or highly conserved like R9 (bold).
