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Syntenic analyses revealed that two RAG genes are physically linked and conserved on the same locus in head-to-head orientation from sea urchin to human for about 550 MY.
Yet another possibility (suggested by Jim Kaufman) is that both types of loci could have existed in the ancestral MHC, but that, after duplication of the whole region, CD1 and classical MHC loci were conserved on the same chromosome in the lineage leading to chickens, but individually on the two separate chromosomes in the lineage leading to mammals.
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The bivalent domains occur at regions on the chromosome where some of the DNA sequence is highly conserved, meaning the same sequence is found in widely differing species.
Based on the consensuse that the 'seed' region (2 7nt in 5' end of mature miRNA) is conserved in the same miRNA family, we used BLAST to search conserved miRNAs against the published miRNA datasets (miRBase release 14.0, September 2009) [50].
We assume that regions conserved among different species are possibly also conserved within the same species.
The residues on both sides of these positions are also conserved, but in the same region other highly conserved amino acids constitute motifs of unknown function.
Most of these species also contain a loosely linked SDMA, separated by 200 500 kb from the conserved cluster but on the same supercontig.
We identified subsequent breast conserving procedures done on the same breast (that is, coded with the same laterality) by using a range of breast operation codes (B28.1, B28.2, B28.3, B28.4, B28.5, B28.8, and B28.9) (see appendix for description of codes).
"They've been designed and constructed and conserved in much the same spirit".
A row of eight conserved shophouses along the same street was given a radical makeover by seven architects.
For this reason, they should display a conserved localization within the same eukaryotic species.
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