Exact(22)
Importantly, HMGA2 is specifically expressed during early stages of embryonic mammogenesis and absent when WNT10B expression is lost, suggesting a developmentally conserved mode of action.
Taken together, the positions of phosphorylatable amino acids in the AL are strictly conserved in PSKRs, suggesting a conserved mode of receptor regulation.
Because the key principles and regulatory components of different intracellular vesicle trafficking events are broadly conserved, the mechanism that we have uncovered is likely to represent a conserved mode of action.
In contrast to Sec7 and Syt1, human ARNO stimulated nucleotide exchange on yeast Arf3 by approximately 11-fold (Figure 4B), indicating that although Yel1 and ARNO are only distantly related at the sequence level, they may share a conserved mode of action towards the Arf6 family of small G proteins that is not shared by other Arf GEFs.
Risk assessment assumes that there is a conserved mode of action and comparable toxic responses between species.
The crystal structure of APLF FHA and triphosphorylated XRCC4 peptide reveals a conserved mode of core pSpT motif binding.
Similar(38)
We develop a Gauss Jordan factorization procedure to explicitly separate the slow (deposition), fast (equilibrium), and instantaneous (conserved) modes of thin-film deposition models describing the dynamics of the precursor, surface, and deposition chemical species, focusing primarily on the dynamics of atomic layer deposition (ALD) processes.
Our sequence comparisons reveal that a majority of the functionally important residues of the Gβγ sequences are identical between Ciona and other organisms including human, indicating highly conserved modes of complex formation.
For MAPK (Ot08g00430) we observed phosphorylation of a conserved Y on the T-X-Y motif of the activation loop (Additional file 6: Figure S4A), which indicates conserved modes of activation.
Furthermore, the elevated transcript levels of the genes associated with anaerobic respiration can allow plant cells to invoke the energy conserving mode of ATP production under submergence stress in Porteresia as speculated earlier.
Crystal structures for these compounds bound to toxin B pentamer revealed a conserved binding mode for the MNPG moiety, with multiple binding modes adopted by the attached morpholine derivatives.
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