Sentence examples for conserved marks from inspiring English sources

Moreover, two specific and universally conserved marks of active or open chromatin, H3K4me and H4K16ac, are absent from telomeres in both yeasts.

H3K4 methylation is an evolutionarily conserved mark, and the degree of this methylation is biologically significant because proteins that interact with methylated histones are able to distinguish between mono-, di-, and trimethylated lysines.

How are conserved epigenetic marks faithfully inherited from one generation to the next?

These conserved epigenetic marks have been found to influence many aspects of gene expression and chromosome biology, and they have characteristic genomic distribution [ 9].

One of the principal and evolutionarily conserved chromatin marks associated with DNA damage that expose DNA ends or single-stranded regions is the phosphorylation of histone H2A on serine 129 by the Tel1 and Mec1 kinases (Rogakou et al. 1999; Downs et al. 2000; Shroff et al. 2004).

Sequence conservation is plotted beneath the alignment and conserved residues marked and color-coded according to the default CustalX settings.

Kbz signals were detected among core histones from all the three species, indicating that Kbz is an evolutionarily conserved histone mark in mammalian and insect cells.

They contain a conserved proline marking the end of helix 8.

These genes encode histone methyl transferases, specifically tri-methylating H4K20, an evolutionarily conserved epigenetic mark for heterochromatin [ 61].

An additional pair of highly conserved paralogs (marked in blue in Fig.  1) was identified in cluster B in both the DM/RH/HB ortho-haplotype and HB-H1.

MLL2 is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family genes and encodes a specific histone 3 lysine 4 (H3K4) methyltransferase, which provides an evolutionarily conserved epigenetic mark for active gene transcription [ 38].