Furthermore, structures of the SRAP domain reveal that the catalytic triad and other highly conserved residues line a conserved structural pocket that could serve as a potential interaction site.
Side chains of seven conserved residues line the substrate cavity in the structures of the soybean isoforms, and these are largely nonpolar.
Authors' response: The TMP was selected because it is typically the longest gene in mycobacteriophage genomes and because regions within TMP gene are conserved (P.6 line 125 .p.7, l. 156.
In the same figure, one can see that CGFS class GRXs have a larger number of positions in the alignment that either have high NMI interaction with other position (black lines and black residues) or are highly conserved (red lines and red residues).
We note that most Piwi proteins displaying t1 preferences have conserved residues lining the t1-binding site (with the notable exception of Mili, which appears to lack several residues homologous to the t1A-binding residues in Ago2).
Finally, the CMV P feature indicates that location 191, which contains a highly conserved Pro-line residue, is specific to the PD-resistant prions (see Fig. 2).
It encodes a broadly conserved, germ line-specific RBP associated with sperm development in most phyla (Haag 2001), but in C. elegans it is required for oogenesis instead (Karashima et al. 2000, Maruyama et al. 2005).
This is also supported by the observation that 79% of total interactions involving genes commonly expressed in the MCF7 and K562 cell lines were conserved among cell lines.
For the two-dimensional case these are two coupled differential equations, which represent the borderline between the resistive but flux conserving (or line conserving) case, and that of reconnective solutions.
In this study, the methylation level of ALVE conserved regions in line 72 was nearly twice to six times as high as that observed in line 63, which is consistent with the hypermethylated retrotransposon frequently found in normal tissues of mammals [11], [40], [41].
