Sentence examples for conserved invariant from inspiring English sources

Although the sequence variable loops of the human immunodeficiency virus' (HIV-1) surface envelope glycoprotein (gp120) can exhibit good immunogenicity, characterizing conserved (invariant) cross-strain neutralization epitopes within these loops has proven difficult.

Several conserved, invariant residues among glucose transporters (namely, GLUT1- GLUT4) were reported for XylE that, when mutated to alanine (Ala), reduce the affinity of substrate binding (highlighted in Fig.  5).

Various options are available, and they vary in cost, accuracy and ability to approximately conserve invariants.

Sites were classified as conserved were invariant across both groups whereas relaxed sites were invariant in reference group A, but variable in analyzed group B, fixed; sites were variable in reference group A and invariant in analyzed group B, and switched sites were invariant within each group, but contained different amino acids.

A number of highly conserved or invariant residues found in the β domain are clustered around the iron sulfur center.

The diversity of the γδ TCR is limited, suggesting that the ligands for the γδ TCR are conserved and invariant.

An alternative splice site was assumed to be conserved if invariant dinucleotides (GU for donor sites and AG for alternative sites) of both alternative sites were conserved.

These findings serve to identify highly conserved and invariant structures as targets for bNAbs that can serve for rational immunogen design through various approaches.

Histone acetylation, arguably the best-studied histone modification, occurs at the ɛ amino groups of evolutionarily conserved, often invariant, lysine residues most often located in tail domains.

This position is conserved but not invariant in MRPS5 orthologues.

We therefore mutated two conserved though not invariant residues (R2510 and R2513) to alanine.