Exact(9)
The nearly complete sequence identity of the 5' ends of these exons over 60 million years of evolutionary time indicates there is a highly conserved interaction between the dumpy message from these regions and proteins involved in the splicing process, possibly in a tissue specific manner [30].
In a screen to identify cellular interactors of IAV NP, we found a novel and highly conserved interaction between IAV NP and host protein Clusterin (CLU).
Essers et al. demonstrated an evolutionarily conserved interaction between FOXOs and β-cat, suggesting the existence of crosstalk between FOXO and Wnt signaling pathways [ 95].
Consistent with that, RNAi of dbl-1, a TGFβ homolog, modestly rescued the lethality of mua-3 mutants, suggesting a potentially conserved interaction between MUA-3 and a TGFβ pathway in C. elegans.
An interolog is a conserved interaction between a pair of proteins which have interacting homologs in another organism.
Here, we use yeast and zebrafish, as well as human in vitro systems, to assess the biological activity of 5-nitrofurans, and we identify a conserved interaction between aldehyde dehydrogenase (ALDH) 2 and 5-nitrofurans across these species.
Similar(50)
The conserved interactions between different species are named interlog [23].
The other highly conserved interactions between the two species are different (Table 2).
Conserved interactions between RecQ helicases and Top3 exist in other organisms as well [ 11- 15].
Paul et al. [ 71] studied Arabidopsis 14-3-3 14-3-3 14-3-3icomplexesed highly conserved interactions betwhichhumans and plants.
When comparing the results of sets 1 and our sequenced miRNA/target, we validated a total of 27 conserved interactions between small RNAs and corresponding transcript genes.
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