Sentence examples for conserved functionality from inspiring English sources

Nevertheless, many related proteins show conserved functionality more in terms of domain and structural conservation.

oryzicola after transfer to rice, suggesting conserved functionality across different genera of grasses.

The analysis based on the conservation of individual binding sites, however, does not address the question whether a promoter or enhancer, which typically have multiple binding sites, would have conserved functionality or not, as the gains and losses of binding sites in the neighborhood may compensate each other so that the overall affinity remains largely unchanged [56], [64], [65].

The sequence homology may result from conserved functionality.

The biological alterations in humanized AVPR1A mice resulted in the rescue of the prepulse inhibition impairments that were observed in knockout mice, indicating conserved functionality.

We shared the initial concern with reviewer 2, which is the reason why we validated the structural models and demonstrated conserved functionality in great detail and at several levels.

It is important to note that some of the pseudogenes with frameshifts in homopolymeric tracts may still conserve functionality (Tamas et al. 2008; Wernegreen et al. 2010).

It has the advantage of offering a strongly regulated in vitro environment, while preserving much of the complex cellular integrity, including cellular barriers and intact circuitry, and as a result conserving functionality – resulting in an in vitro environment more comparable to the in vivo brain than seen in the homogenate method.

This suggests an explanation for their high abundance in genomic regions and low abundance in coding regions, which must be conserved to maintain functionality.

Afterwards, the superfluous copy(ies) may have been transformed into a pseudogene, whereas the original copy could have conserved its functionality (therefore leading to no changes in the gene order).

Similarly, the acidophilic caspase family cleavage site motifs are often lost in orthologous proteins, however, are gained in different members of a targeted pathway thereby conserving network functionality [ 34].