Sentence examples for conserved function and from inspiring English sources
Given the deep divergence of D. melanogaster from B. mori, which last shared an ancestor approximately 330 million years ago (Wheat & Wahlberg, in review), the only genes likely to be functionally annotated are those with highly conserved function and constrained evolutionary dynamics.
The author has previously noted [67] that improved search algorithms based upon conserved function and "information content" are needed to assess similarity of proteins in cases in which strong evolutionary selection is suspected.
Members of RH have been identified in all plasmodium species so far analyzed indicating the conserved function and importance of this protein family to the malaria parasite [1].
ddTpp1 and human TPP1 localize to the lysosome in Dictyostelium, indicating conserved function and trafficking.
It is possible that bm047 has a conserved function and has not diversified into a multi-copy gene family.
Conversely, genes with conserved function and regulation can be used to infer DNA sequence changes that are either neutral or that coevolved to maintain the selected characters.
However, together with the loss of function upon deletion of the IgC2 domains, the relative conservation of the IgC2 domains of epithelial CEACAMs may reflect conserved functions and therefore evolutionary constraints on this region.
This result suggests conserved functions and a general expression pattern of the Paramecium Hsp70 gene family, at least between P. caudatum and P. tetraurelia.
In summary, our data indicate that JMJD6 has conserved functions and often affects similar pathways in a congruent manner across multiple cell types and at a gene-expression and phenotypic level.
Distinct from the canonical CNLEDVID genes are those with a CC-domain similar to RPW8, that are suggested to have conserved functions and can be found throughout the plant kingdom [ 6].
The fundamental assumption underlying an annotation transfer protocol is that evolution conserves function, and that sequence similarity implies homology (i.e. a common ancestry) and can thus be used as a basis for inferring function.
