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Here we analyze this problem based on a model that captures the PTTRS' conserved features.
Sequence analyses revealed distinctive, conserved features that distinguish trimerising and pentamerising CCDs.
Our study revealed conserved features of panicle-associated 21-nt phasiRNAs and associated loci between Oryza species.
This cross-species activity of Cas5d provides a special opportunity for elucidating conserved features of the CRISPR RNA processing event.
Conserved features in retinal design have enabled detailed analysis and comparisons of structure, connectivity and function across species.
Because small molecule modulators are designed to target conserved features of a protein, they are usually effective across species.
Nevertheless, after coarse-graining the flexibly correlated regions into contiguous stretches, we identified conserved features presumably needed to support common functional requirements of these two proteins.
Conversely, most single point mutations throughout key conserved features in peripheral tertiary architecture supporting the SAM binding pocket have relatively little impact on riboswitch activity.
These viruses had conserved features (e.g. predicted protein cleavage sites, presence of a leader protein, 2A, 2C, 3C, and 3D functional domains), suggesting they have a common ancestor.
Thus a detailed knowledge of the diversity and physiology of rumen methanogens is required to define conserved features that can be targeted for methanogen inhibition.
Remarkably, the IRES elements of these insect viruses can also function in mammalian cells suggesting that they interact with highly conserved features of the eukaryotic ribosome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com