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Evidence that flexibility is a functional characteristic that needs to be maintained came from studies on a family of flexible linkers in the 70 kDa subunit of replication protein A (RPA70), which display conserved dynamic behavior in the face of negligible sequence conservation.
Autophagy is an evolutionarily conserved dynamic cellular catabolic process.
While these results cannot entirely exclude an effect of genetic drift, they strongly point to an evolutionary conserved dynamic role of AVP along a continuum, with hypomorphic Avp alleles finally contributing to low anxiety- and possibly depression-like behaviors and hypermorphic alleles contributing to hyper-anxiety.
These results support the hypothesis that these residues form a conserved dynamic hinge, enabling modulation of the size of the fatty acid binding pocket.
Recent studies of the molecular basis of SULT substrate specificity reveal that SULTs extensively utilize a conserved, dynamic 30-residue active-site "cap" in selecting their substrates.
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Comparisons with previously published studies of C. elegans GLD-1 targets reveal both conserved and dynamic targets.
The crucial point is that unless the qubit is measured, the amount of "hidden" information it stores is conserved under the dynamic evolution (namely, Schrödinger's equation).
These links are provided in part by vinculin, a highly conserved and structurally dynamic protein that stabilizes adhesions complexes [1] and which binds to actin through the agency of its five-helix bundle tail (Vt) domain [2].
Our genome-wide RAD21 binding survey in ESCs and EBs revealed three modes of RAD21 binding, the conserved and the dynamic CTCF dependent and the CTCF independent binding mode.
Our findings indicate that SAR11 genomes from different oceanic provinces share many conserved features despite dynamic processes of genome change that are at work in nature.
The contradictory findings on the protosplice site involvement versus the evolution of these motifs after intron gain (in which case 'protosplice site' becomes a misnomer) might reflect objectively existing differences in the evolution of the gene architectures among gene families, in particular between highly conserved and more dynamic families.
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CEO of Professional Science Editing for Scientists @ prosciediting.com