Exact(13)
We look at overall properties of a subset of predicted human binding sites that are conserved down to chicken, fugu or danio and we concentrate on conservation of the simplest network motif.
The runt domain is highly conserved down to Drosophila [ 11].
The L66 residue was also observed to be highly conserved down to Candida tropicalis.
This is a superfamily of secreted and membrane-bound proteins with SRCR domains that are highly conserved down to sponges [ 26, 27].
The R213 residue is highly conserved down to Drosophila and bioinformatic analysis indicated it was very likely to be pathogenic (Table 2).
Thus, based on sequence homology alone, it seems that the Dp140 isoform is likely to be conserved down to amphibia, but not fish.
Similar(45)
Comparison with human datasets revealed conserved up-regulation of ribosome, lysosome, and complement activation and conserved down-regulation of synapse, mitochondrion, proteasome, and spliceosome.
In contrast, genes encoding cell wall proteins, fatty acid desaturation functions and oxidative pentose phosphate pathway proteins showed a conserved down-regulation response to bacterial, fungal and parasite infection (green; Figure 6).
While there is a wealth of information about conserved down-stream signals affected by DLK-1 activity, very little information exits about how DLK-1 itself is activated (Tedeschi and Bradke, 2013).
Each relaxation is designed both to smooth the mesh and to conserve down to round-off error the area or volume enclosed by the curve or surface.
Conserved down-regulation of cytochrome associated proteins, cytochrome aa3 controlling protein and cytochrome c oxidase subunit II, may represent another cellular mechanism to restore the electron flow balance.
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