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Through the application of an extensive filtering method [ 18] on the selection of transcription factor binding sites (TFBS), a conserved distant regulatory module was identified within the upstream region of some Wnt5 genes.
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Identification of the new snoRNAs is usually reliant on predicted conserved target sites, which however appear only partially conserved across distant organisms.
Therefore the complementation of the creB1937 mutation by cre2 is of importance as it demonstrates that the CreB/CreC complex previously identified in A. nidulans, and also the targets of CreB deubiquination, are conserved between distant filamentous fungi despite relatively low conservation outside of the ubiquitin C-terminal hydrolase domain.
Even though not all yeast SL pairs are expected to be conserved in distant organisms, those associated to essential functions have a higher conservation probability.
The regulatory model predicts that AS-NMD candidature should be conserved among distant species [12].
In this paper, we show that the fundamental function of the TMD of Sec61β is conserved among distant species.
This weighting scheme assigns a higher weight to motif sites conserved in distant orthologs in their contribution to the motif WM than to sites conserved in close orthologs.
RP1L1 was found to be conserved in distant vertebrates [ 8].
Some miRNAs are remarkably conserved across distant orders, suggesting conserved evolutionary functions.
Clear orthologs of non-classical class I are conserved in distant marsupial lineages.
This 60 aa domain is highly conserved across distant species from insects to mammals [ 20].
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