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Such properties are also observed for some restriction endonucleases like FokI, MboII or MlyI which bind a specific target sequence and cleave at a conserved distance from this binding site [35].
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This is a well written paper reporting, unexpectedly, that a human sHsp highly conserved histidine some distance from the alpha-crystallin domain dimer interface, modulates the stability of that interface as a function of pH, over a physiological range.
We found that microsatellites near the transcription start sites of genes are often highly conserved, and that distance from a microsatellite to the nearest transcription start site is a good predictor of the microsatellite conservation score.
In Figure 7 we show PKA and Akt with bound substrate peptides and display variability in the context of proximity to the substrate and distance from conserved residues.
Response: The "Results" do not just state the fact of the widely conserved promoter and its distance from the gene (which is indeed evident from Table 1) but also comparisons of the orthologous gene promoters supported by the alignment analyses and interpretations of published data.
Maintain your distance from the student.
For all chromosomes, the minimal distances of phylogenetically conserved genes from the chromosome ends (i.e., Pf1 through Pf4) are larger than 50 100 kb.
Axonal growth cones navigate to their target over large distances with a precision and timing that is highly conserved from animal to animal.
Interestingly, the distance from the end of ACD to the end of the motif is well conserved.
We numbered the four exons conserved between human and mouse as exons -1, -2, -3 and -4 (in order of increasing distance from the translation initiation site).
The order, relative distance from each other and strand orientation of each putative TFBS that comprised a core module were remarkably conserved within each COG.
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