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Dehydrin proteins (DHNs) are part of a conserved cell protecting mechanism in plants although their role in stress tolerance is not well understood.
Apoptosis is a highly conserved cell death pathway that regulates tissue homeostasis and normal development.
Prion protein (PrPC) is an evolutionarily conserved cell surface glycoprotein expressed abundantly on neuronal cells.
Metacaspase proteases have since been characterized as apoptotic regulators in plants, fungi and protozoa supporting the concept of a widely conserved cell death pathway [4], [5].
This finding was relatively expected, as the discussed factors are recruited to cellular processes which appear to be common to all deuterostomes, and even more so, have been suggested to reflect conserved cell type differentiation in the last common bilaterian ancestor [61].
A comparison of the TAP-tagged data from a combined analysis of 129 TAP-tagged rice protein kinases with a concurrent screen using yeast two hybrid methods identified an evolutionarily new rice protein that interacts with the well conserved cell division cycle 2 (CDC2) protein complex.
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We confirmed that lin-41 mutant oocytes prematurely enter M phase by disrupting conserved cell-cycle genes.
Recognition receptors (called pattern recognition receptors; PRR) detect pathogen-associated molecular patterns (typically conserved cell-surface motifs), and signal this to modulating signalling receptors.
Notch signaling is a highly conserved cell-cell interaction mechanism with a relatively simple molecular architecture but a diverse, cell context-specific, signaling output [ 4, 5].
Notch pathway is a highly conserved cell-cell communication pathway and functions to regulate many different cellular processes during embryonic development and in adulthood [ 26].
Together with the decrease in E-cadherin, we observed more disorganized ß-catenin localization at cell-cell contacts in RhoB-depleted cells that still conserved cell-cell adhesions.
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