These 61 uORFs, taken from 43 genes, therefore represent a subset that is highly conserved both in terms of absolute and relative conservation of their UTRs, and in terms of specific conservation of the uORF in closely related species.
Moreover, for additional analyses, the lists of 'highly conserved targets' were defined as mRNAs with a specific binding site conserved both in mammals (humans, mice, rats, dogs) and in chickens.
Comparative analyses of rtx gene among five strains show a high level of conservation and the genes located at 5' of rtx, are strictly conserved, both in sequence and order, whereas the synteny, and sometimes nucleotide similarity, of those located at 3' do not follow the same pattern (see Additional file 3).
Its presence is well conserved both in lower and higher eukaryotes.
Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure.
In this study we have conserved both space and time complexity.
Kinetic data, both steady-state and transient-state, and X-ray crystal structures indicate that these enzymes are highly conserved both in mechanism and in structure.
The major interactions around TCL due to the aromatic(cation)–aromatic and hydrogen bonding interactions are found to be conserved both in WT and mutant complexes.
As noted above, Leibniz maintains that vis viva is conserved both locally in particular cases of impact, and globally in the created world taken as a whole.
Figure S2 shows that this region is conserved both in the 3' direction to include most or part of intron 1, and in the 5' direction.
Core carotenoid biosynthetic proteins (CrtB and CrtI) are highly conserved both functionally and phylogenetically (Figures 2 and 3), consistent with their identification with the "root" of the carotenoid tree-like hierarchy.
