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Presumably, this configuration preferentially 'exposes' the terminal PPT and renders it accessible to RH for precise cleavage, which will automatically generate the highly conserved attachment site.
Putative phage sequences were predicted in the genomic sequences of W. ceti strains WS74 and WS105 using PHAST [ 31], and then GLAM2 (Gapped Local Alignment of Motifs) was used to identify the conserved attachment sites for the predicted phages [ 32].
Taken together, these observations suggest recent horizontal acquisition and dissemination of vcrABC across all Dehalococcoides ecotypes by way of a ssrA-specific mobile element with conserved attachment site and integration module.
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The basic membrane fusion reaction is mediated by evolutionarily conserved soluble NSF attachment protein receptors (SNAREs) and related proteins like Munc13 and Munc18 (Weber et al., 1998; Sudhof, 2004; Brunger, 2005; Jahn and Scheller, 2006; Lang and Jahn, 2008; Jahn and Fasshauer, 2012).
Ipl1/Aurora B is a highly conserved kinase that corrects attachment of sister kinetochores that have attached to the same spindle pole, whereas Spc24 is a component of the conserved Ndc80 kinetochore complex that attaches directly to microtubules.
This suggests that the triggers for spore activation and, to a lesser extent, for attachment are phylogenetically conserved.
The in situ reconstructions of the Yersinia and Shigella injectisomes show high overall similarity considering the lower resolution of the Shigella injectisome: the overall dimensions, ring hierarchy and the peptidoglycan attachment location are conserved.
The expressed recombinant RBD region of the type II FCoV S protein, bearing one-tenth of the authentic S protein critical in both virus neutralization and cell attachment, is highly conserved among FCoV, TGEV and CCoV [ 17].
In addition, point mutations of conserved amino acids around the EPG attachment site didn't prevent EPG modification, indicating that a specific primary sequence does not appear to be involved in EPG attachment.
The surgical technique presented here removes the corpora cavernosa of the clitoris, but conserves important neurovascular attachments.
As Drosophila also encodes an ortholog of VAB-19, the EPS-8/VAB-19 interattion at cell matrix attachments could be phylogenetically conserved.
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