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Despite the fundamental importance of OXPHOS to aerobic life, mt protein-coding genes are not highly conserved and evolve at rates that is 5 50 times that of typical nu genes in vertebrates (Lynch 2007).
Our analyses show that genes closer to origins of replication are more highly conserved and evolve more slowly than genes distant from an origin of replication, which evolve more quickly and are more dispensable.
In some species, such as Arabidopsis, Brassica or Silene, the divergent parental rDNA sequences remain conserved and evolve independently in hybrids without any interaction [25] [27].
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Links to gene families in rice, Sorghum bicolor, Zea mays and Arabidopsis thaliana are provided to facilitate analysis of how genes are conserved and evolved among plant species.
As reported previously the unique sequence of the Xist gene is not conserved and evolves very rapidly [2], [15].
These events were also more conserved and evolved less with time.
This is expected since these genes are known to be highly conserved and evolving more slowly than other genes in the bovine genome [ 82].
Our results showed that the eight COG subunits seem to be conserved and evolving under strong purifying selection, in order to maintain the integrity and function of the complex.
However, functionally important DNA segments are not always strictly conserved, and can evolve due to a variety of factors, including positive selection [ 8- 11].
Global analysis of evolution rates of hibernation-related genes in bear showed that they are largely conserved and slowly evolving genes, rather than novel and fast-evolving genes.
We investigate conserved and convergently evolved features within these proteins and compare these to the features of classic coiled coil proteins including tropomyosin and leucine zippers.
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