Sentence examples for conserved active from inspiring English sources
Such a tool is useful as conserved structural entities can point to conserved active sites indicating common function, evolutionary links and drug binding targets for therapies.
Class II sites highlight evolutionarily conserved active enhancers that direct chondrocyte-related gene activity through the direct binding of Sox9 dimer complexes to DNA.
The highly conserved active motif is denoted in yellow underline (Figure 2A).
The deduced amino acid sequence containing highly conserved active site motif Cys62-Gly-Pro-Cys65 Cys62-Gly-Pro-Cys65 Cys62-Gly-Pro-Cys65 Cys62-Gly-Pro-Cys65
A great challenge remains in the design of selective PTPs inhibitors due to their highly conserved active site.
In previous work, structure-based functional site descriptors, fuzzy functional forms (FFFs), were developed to recognize structurally conserved active sites in proteins.
Meanwhile, the highly conserved active site residues make it a great challenge to widen the substrate spectrum of nitrile reductase by means of protein engineering approaches.
Both subdomains contain conserved active-site motifs.
As expected, at least one conserved active-site arginine was detected in all cyanobacterial PRXs.
Conserved active-site residues in the Rab switch II region stabilising the nucleotide-free form differentiate these pathways.
All PRXs share a highly conserved active-site arginine, which would lower the p Ka of the peroxidatic cysteine somewhat by stabilizing its thiolate form (see review [ 41]).
