UBL domains found in USPs are relatively poorly conserved and a common function is not known.
The intron positions of DmGSTS1 and A gambiae GSTs1-1 are conserved indicating a common ancestor for these genes.
Overall, the protein architectures of closely related members in a specific clade were remarkably conserved, indicating a common origin and/or close relationship.
An example of such Ultra-CNMSs was shown in Figure 5C, and the three homologous CT repeats were highly conserved from a common ancestor over 48 Myr.
Genes involved in centriole biogenesis, either regulatory or structural, are generally well conserved, suggesting a common assembly pathway across species (Carvalho-Santos et al, 2010).
In summary, these results indicate that the chromosomal organisation of akirin-containing tracts of vertebrate genomes were conserved from a common ancestor prior to the speciation events separating the major vertebrate classes.
Because in class XI myosins the tail sequences C-terminal to the coiled-coil regions are highly conserved suggesting a common domain we reassessed the definition of the DIL domain.
This inconsistency between the current phylogeny including AA1_3 and the traditionally-accepted phylogeny of A. delicata poses a number of questions. A. delicata is one of the earliest branching Agaricomycete lineages, meaning that AA1_3 could either have been inherited and conserved from a common ancestor or acquired by horizontal transfer [ 62].
For Arabidopsis-Brassica orthologous CNMS gene pairs, the frequency distribution showed a clear peak for Ks values of 0.4 to 0.5, suggesting that these CNMSs were conserved from a common ancestor over a 15 million years (Myr) period, which was consistent with the divergence time frame estimated at 14.5 to 20.4 Myr based on mitochondrial DNA data [ 23].
Our results indicate that not only was a trend conserved for the dose responsive effects, but also a time –responsive up and down-regulated trend among these compounds was conserved, implicating that a common underlying mechanism may be shared by these compounds.
