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Fortunately, the usual parsimony procedure will automatically conserve sequence correlations between pairs of positions and hence the predicted nodal sequences will usually satisfy secondary structure requirements.
UrtR homologues conserve sequence in helices α3 and α5; α3 contains residues involved in ligand binding by HucR and PecS, and α5 is the DNA recognition helix.
By design, these jumbles are not constrained to conserve sequence, particularly the critical active site motifs of the two classes of aaRS.
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21 For miRNAs that do not have conserve sequences, noncomparative methods are needed.
The latter include both the conserved CpG pattern and other fully conserved sequence motifs.
Because DNA is always subject to mutation, a highly conserved sequence is a sure sign of DNA that plays some vital role.
Conserved sequence elements are highlighted and identical residues were showed in the consensus line.
Conserved sequence motifs guide the rational design of light-regulated variants of histidine kinases and other proteins.
TMEM176 sequences have regions of highly conserved sequence with MS4A.
conserved sequence regions to allow development of degenerate primers.
Figure 2 shows the multiple alignments of the highly conserved sequence of GK1.
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