Sentence examples for conserve regions from inspiring English sources
To test if nucleic acid-based CTLA-4 inhibitors could be developed into a novel adjuvant, we designed two oligonucleotides, CMD-1 and CMD-2, with the sequences complementary to the conserve regions identical between human and mouse CTLA-4 mRNA 3′ untranslated region (3′ UTR), and tested their in vitro effects on CTLA-4 production and their adjuvanticity for vaccines in mice.
The deduced amino acid sequences from 9 genes sequences were aligned by Mega 4. Amino acids that are identical between CSN and other sequence are shaded in black and the two conserve regions are underlined.
Pictures containing the faces of healthy relatives (or others) were either discarded or cropped to only conserve regions with the patient face.
While it is imperative to conserve tropical landscapes, which generate a lot of diversity, our results suggest that it is also important to conserve regions of relatively low diversity as they may contain assemblages that have unique evolutionary histories.
Class 1, 2 and 3 integrons were initially detected by PCR using degenerate primer set hep35 and hep36 (Table 1), which hybridizes to conserve regions of integron-encoded integrase genes intI1, intI2, and intI3[ 21].
To confirm the knockdown efficiency, eight plants with virus symptoms were randomly selected from each of the two BSMV treatments, and their transcript levels of TaATG6s in the fourth leaves were determined using qRT-PCR as described above with a primer pair (Additional file 2: Table S1) designed to conserve regions in the three wheat ATG6s.
This happens, for example, when the sequences to be compared include highly conserved regions intervened by conserved and unconserved ones.
Unexpectedly, we observed that LD was significantly weaker in conserved regions than in non-conserved regions.
While the epitopes derived from sequentially conserved regions may undergo mutations, it is worthwhile to explore the structurally conserved regions as a new dimension for epitope prediction.
Finally, based on the alignment, the coordinates of the model were constructed for the structurally conserved regions of the model.
Poorly conserved regions of primary structure are peripheral to an essentially identical catalytic core.
