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In addition, we could add the caspase activation assay to the same wells as the real-time cell viability assay, to very conveniently analyze the same cells with both assays and conserve cells and reagents.
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T lymphocytes expressing γδ T cell antigen receptors (TCRs) comprise evolutionarily conserved cells with paradoxical features.
A unified method for simulating multiphase flows using an exactly mass, momentum, and energy conserving Cell-Integrated Semi-Lagrangian advection algorithm is presented.
Apoptosis or programmed cell death is a highly conserved cell death mechanism and has a significant role in embryonic development as well as in the initiation and progression of several diseases.
The Notch signaling pathway is a highly evolutionarily conserved cell-cell contact-dependent signaling mechanism, which is activated when a ligand binds to a Notch receptor, leading to receptor cleavage and the release of the Notch intracellular domain (Notch ICD).
Dehydrin proteins (DHNs) are part of a conserved cell protecting mechanism in plants although their role in stress tolerance is not well understood.
The canonical Notch pathway with four Notch receptors (Notch1-4) and five ligands (DLL1, 3-4, Jagged 1-2) is an evolutionarily conserved cell signaling pathway that plays critical roles in cell-fate determination, differentiation, development, tissue patterning, cell proliferation, and death.
The close homology of the basic region/leucine zipper (bZIP) DNA-binding and dimerization domain of HLF to that of the CES-2 cell-death specification protein of Caenorhabditis elegans suggests a model of leukaemogenesis in which E2A-HLF blocks an early step within an evolutionarily conserved cell-death pathway.
Prion protein (PrPC) is an evolutionarily conserved cell surface glycoprotein expressed abundantly on neuronal cells.
Apoptosis is a highly conserved cell death pathway that regulates tissue homeostasis and normal development.
Metacaspase proteases have since been characterized as apoptotic regulators in plants, fungi and protozoa supporting the concept of a widely conserved cell death pathway [4], [5].
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