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Interestingly, the dN/dS ratios in these conserved regions were low, suggesting that positive selection pressure in speG operates to conserve a function other than superantigenic activity, because none of the SDSE clinical strains expressed SpeG proteins [ 13- 15].
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Recent data strongly suggest that the retromer complex has conserved a function in mediating retrograde trafficking [ 38] and that VPS29 is involved in the cycling of certain PM proteins and required for the establishment of cell polarity during organ initiation in plants [ 66].
Whereas the B, C and E functions are regarded to be broadly conserved, the A function in specification of the perianth is not widely observed and questioned in Antirrhinum [ 52, 53], as well as other plants [ 54].
Specifically, we modelled the probability that a given splice site is conserved as a function of the gene's fold-change in expression and maximal level of expression across all stimulations.
Dehydration tolerance is the plant's capacity to sustain or conserve plant function in a dehydrated state.
All other domains in PRDM9 are conserved among species, suggesting that a conserved biochemical function is tethered to a rapidly evolving DNA-binding specificity.
Taken together, our results further support a conserved enzymatic function of Jmjd6 most likely as a classical non-heme, Fe(II)- and 2OG-dependent dioxygenase.
Of the 177 human orthologues, 26 inhibited aggregation in the HK293 cells supporting the idea that genetic regulators identified in C. elegans would have a conserved function relevant for a human model [ 23].
Schotta, G., Ebert, A. & Reuter, G. SU VAR 3-9is a conserved key function in heterochromatic gene silencing.
In addition, the mouse homolog of Shopper, Suox, is significantly enriched in glial cells compared to neurons30, suggesting that sulfite oxidase may have a conserved glial function.
The ability of HCF proteins to stabilize this VP16-induced complex has been conserved in diverse animal species including Drosophila melanogaster and Caenorhabditis elegans suggesting that VP16 targets a conserved cellular function of HCF-1.
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