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For that reason we chose a conservative statistic.
Hedges' g is a more conservative statistic, appropriate for wider generalization.
This conservative statistic takes into account the structure of bound regions across the genome in assessing the significance of overlaps.
As the percentage error from measurement uncertainty can be quite high for some media components [ 18], the median of relative deviations was chosen as a conservative statistic that could still be capable of identifying systematic error.
It is of interest to note that the posterior probability score using a target fold difference factor of 2 was the most conservative statistic producing a list of 424 genes with a posterior probability cut-off of >= 0.9.
Similar(55)
The IDI is often more sensitive than the rather conservative C statistic because when several highly predictive markers are in the model, enormous odds ratios are required to meaningfully increase the C statistic (17).
A full mixed-effect analysis could improve the power of the inference but this is not necessary because we already have significant results using the more conservative summary-statistic approach (Penny and Holmes, 2006).
Ignoring very small entries in the matrix leads to a more conservative test (the test statistic is smaller, which results in higher P-values).
To be conservative, the LRT test statistic was assumed to follow a χ 2 distribution with one degree of freedom rather than the appropriate mixture distribution [ 46].
This statistic is conservative and allows for the direct comparison of the number of instances an effect was observed in treated versus untreated animals.
Consistent with the more conservative nature of this statistic, eight regions are consistent with a hitchhiking model in D. miranda and three regions remain significant in D. pseudoobscura (table 1).
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CEO of Professional Science Editing for Scientists @ prosciediting.com