Sentence examples for conservative changes of from inspiring English sources

We show how conservative changes of only one or two amino acids result in dramatic changes in quaternary structure, in which the assemblies can be switched between two very different forms.

In mouse and rat, two TAAR7s have conservative changes of Asp3.32 to Glu3.32; the effect of this substitution is unknown as ligands have not been found for Glu3.32-containing TAARs.

Using Moser's theorem (see [15]), there is a smooth conservative change of coordinates φ p : U p → T p M such that φ p ( p ) = 0 →.

Remark 3.2 From the Moser theorem (see [15]), there is a smooth conservative change of coordinates φ x : U ( x ) → T x M such that, where U ( x ) is a small neighborhood of x ∈ M. Proposition 3.3 If f ∈ int IS μ ( M ), then every periodic point of f is hyperbolic.

From the Moser theorem (see [21]), we can find a smooth conservative change of coordinates φ x : U ( x ) → T x M such that φ x ( x ) = 0, where U ( x ) is a small neighborhood of x ∈ M. Lemma 5.4 If f ∈ int CWE μ ( M ), then f ∈ F μ ( M ).

The conservative change of K46R results in a ∼44-fold reduced Cys-tRNAPro deacylation activity as compared to WT YbaK.

In contrast, the activity of the Y195F/V266H variant was ∼2600 times lower than that of the wild type, demonstrating that steric clashes introduced by H266 are not relieved by the conservative change of tyrosine to phenylalanine versus tyrosine to alanine.

However, the possibility of a conservative change of glycine (nonpolar, uncharged) to serine (polar) to modulate the susceptibility level of individuals exposed to this xenobiotic cannot be ruled out without proper functional assays with the arsenic-exposed individuals.

The conservative change of this second residue, V to L, among dinoflagellate taxa (and V to I in the genomic sequence for C. cohnii) supports the inference that this region likely represents protein-coding sequence rather than UTR.

Both Y195A and Y195F mutants were made in the context of V266H to determine whether the smaller Y195 to alanine mutation would lead to greater restoration of activity or if it would instead be a change that was too drastic relative to the more conservative change of Y195 to phenylalanine.

And Mr Gingrich's Republicans were pushing for a broad set of coherent conservative changes to the budget.