Sentence examples for conservation to predict from inspiring English sources
For good information-rich motifs, however, it might not be necessary or even beneficial to use conservation to predict binding sites.
Like PolyPhen and PANTHER, SIFT uses sequence conservation to predict functional consequences, but differs in the way it assembles protein alignments.
In addition, efforts have been made to use functional and sequence characteristics, such as GO annotation and sequence conservation, to predict cancer genes and cancer mutations [ 13, 14].
Furthermore, using Normal Mode Analysis we estimated the effect of ligand binding on overall protein flexibility, a measure which has been used in combination with structural conservation to predict the location of allosteric sites [ 13].
psRobot uses a modified Smith-Waterman algorithm and target site conservation to predict targets in A. thaliana, Brachypodium distachyon, Carica papaya, O. sativa, Populus trichocarpa, Sorghum bicolor, Vitis vinifera and Zea mays.
SIFT makes use of sequence homology and median evolutionary conservation scores to predict conserved protein function.
Why is household energy consumption and conservation difficult to predict from either core values or material interests?
Next, we develop a new method, PIPES (probabilistic integration of PBM, epigenetics and sequence data), to combine the results from the PBM model with DNase I hypersensitivity (DHS) data and evolutionary conservation data to predict tissue-specific TFBS in vivo.
5 predicted interactions (ELK1 GABPA, ELK1 CREB1, ELK1 NFY, ELK1 MYB1, NFY:VDR) from our network could be found in the interacting TF pairs in bone marrow described by Yu et al. Hu and Gallo [ 13] employ a functional conservation approach to predict interacting TFs from tissue-expressed genes.
One study combined pocket prediction with evolutionary conservation in order to predict binding sites for an arbitrary small molecule (Huang and Schroeder, 2006).
The features of the explicit alternative splicing prediction methods: k-mer counts, exon lengths, and sequence conservation are used to predict multiple splice sites and intron retention events along with cassette exons and constitutive exons.
