Sentence examples for conservation tendencies from inspiring English sources
The theoretical basis of LAG is that the residue conservation tendencies are similar and the locations of domains are closely related to the length of protein sequence in the same family [24].
Since these "uncharacterized" genes had low sequence conservation tendencies, we eliminated them from the control gene set.
The protein conservation tendencies were examined in a similar manner to those of the promoter conservation, using protein sequences obtained from the RefSeq database.
From Tables 1, 2, 3 and 4, the terms that have significant conservation tendencies for both protein sequences and promoter sequences were extracted and compiled as a 2 by 2 cross table (Table 5).
This assessment framework of coastal habitat degradation would characterize the landuse change trend, realize better coastal habitat degradation assessment, reveal the habitat conservation tendency and distinguish intensity of human disturbances.
When we examined the promoter conservation tendency for each GO term, by using alignment length or percentage identity as a measure of conservation, the tendencies were consistent with each other (Additional file 11).
Besides the protein conservation, we examined the promoter conservation tendency for the two subsets of the C:ribosome category, cytoplasmic and mitochondrial ribosomal proteins.
Rate4Site is an accurate and sensitive method for calculating the evolutionary rate at an amino-acid site to evaluate the residue conservation tendency (51).
Notably, the general protein conservation tendency described in previous sections holds here: proteins in the cytosol show high protein conservation, while proteins in membrane-bounded organelles, such as mitochondria, have low protein conservation.
Therefore, missing data is unevenly distributed across multiple sequence alignments, and ignoring it is likely to lead to biased conservation scores, in which the scores computed at a region with misalignments are an over-estimate of the true conservation tendency.
Essential orphan genes would be ideal targets for the highly specific identification of all E. coli serotypes, but comparative genomics has revealed a clear conservation tendency of essential E. coli genes throughout the bacterial kingdom [ 31].
