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The evolutionary relevance of this factor is supported by the skewed distributions of UIR size conservation, strong functional (GO) and expression biases that vary with UIR size, and a number of exaggerated gene structure and sequence characteristics.
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DPGs are abundant among eukaryotic genomes and highly conserved; the conservation is stronger within lineages than between lineages.
They imposed energy conservation to strong flow contractions and momentum conservation to mild flow contractions and expansions.
Amino acid conservation was strong on both positions (86% for βThr656Ile and 100% for γPro674Ser, Additional file 1: Table S1).
The short branches at the tips of the tree indicate high sequence conservation and strong evolutionary relationships among subfamily members.
The far-sighted companies we work with are playing the long-game by demonstrating that business and conservation are strongest when they work together.
For SH3-recognized SLiMs, conservation was strongest in cytoskeletal and cytoskeletal-associated proteins.
This remarkable conservation is stronger for the membrane-proximal region than the membrane-distal region.
The desire to engage in subsidized conservation was stronger (M = 4.00) than the desire to engage in non-subsidized conservation (M = 2.80).
Any arguments that an increase in targets may be an artifact of stronger conservation is circular in general – stronger conservation could both be the cause for more predictions, or caused by the presence of functional target sites.
Compared to microRNAs or snoRNAs that exhibit strong conservation across diverse species, lncRNAs lack strong conservation, which is often cited as evidence of nonfunctionality [ 2, 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com