Sentence examples for conservation secondary from inspiring English sources

Figure 5 lists for TrpB the MSA, residue conservation, secondary structure and the location of the interface area.

Aside that, the diversity of sequence predictors with different sequence property measure (sequence conservation, secondary structures, globularity, complexity) also allow for a multi-dimensional coverage of fold-critical residues.

For each position in a MSA, residue conservation, secondary structure, the location of the interface area, active sites and residues, which are characteristic for sequence types, were determined and plotted.

Despite the evolutionary conservation of conserved secondary structures (CSSs) a considerable amount of variation in CSS sequences exist in the genomes of human populations.

The fact that large parts of UGTs seem to undergo neutral evolution, fits with the fact that UGTs generally have low sequence conservation albeit conserved secondary and tertiary structures [ 40].

For each fragment, calculated parameters that include measures of the thermodynamic stability (z-score [ 45]) and conservation of secondary structure are used to make predictions based on a support vector machine (SVM) trained on known ncRNAs, which generates a probability classifier (p-class, scale of 0.0 to 1.0) for the fragment containing conserved secondary structure.

We propose that conservation of secondary structure of the well-conserved domains (defined by sequence conservation and the presence of highly conserved amino acids) probably reflects conservation of catalytic functions and/or protein-protein interactions of these domains.

The obvious conservation of secondary structure in tRNA-related regions including conserved A and B boxes of the split promoter in HAmo SINE manifested their functional importance for transcription by polymerase III.

Secondary structure information of S. tuberosum AGPase SS was used for analysing the conservation of secondary structure elements which in turn provides the functional characteristics.

Computational approaches such as RNAz (Washietl et al. 2005b; Washietl et al. 2005a) and EvoFold (Pedersen et al. 2006) have employed evolutionary conservation of secondary structures, thermodynamic stabilities, and phylogenetic sequence analysis to predict tens of thousands of conserved RNA secondary structural elements in the human genome.

We first identified non-exonic sequences that are most likely to encode functional ncRNAs (functional transcripts that do not encode proteins) by using the program QRNA, which searches for conserved regions with compensatory mutation patterns that are consistent with the evolutionary conservation of secondary structure in functional noncoding sequences [ 14].