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The two independent methods, close and remote species comparisons, presented here suggest the conservation pressure is prominent upstream rather than downstream of the PAS, thus the rest of the analysis will concentrate on the upstream region only.
A related method to determine evolutionary conservation pressure was employed in [ 13], which measured the presence of orthologs in a set of five higher eukaryotes (not considering their phylogeny).
Together, these data indicate that the Early gene promoters may be under selective conservation pressure to contain NF-κB-binding sites, whereas the Late gene promoters may not be.
It is inspired by machine learning techniques for matrix completion applied in other settings [ 37], and in our case we are able to take advantage of specific patterns linking conservation pressure to a predicted observed state.
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However, this debate stresses that international conservation pressures exist for increased predator conservation.
Johan du Toit also illustrates the multi-scalar nature of conservation - whereby global drivers can cause local conservation pressures and/or local conservation can have consequences beyond the spatio-temporal scale of the problem.
While the second prediction is intuitively reasonable, it is in fact rarely satisfied in actual organisms, especially for small genomes (such as prokaryotic genomes), where conservation pressures are very high and specific structures such as operons survive across broad ranges of evolutionary divergence.
Based on the mass, momentum and energy conservation, a pressure and temperature coupling model is developed.
However, this method suffers from problems with mass conservation and pressure oscillations.
The correlation model was established based on energy conservation and pressure balance laws.
Every point of the flow is correctly described thanks to a mixture equation of state based on energy conservation and pressure equilibrium.
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CEO of Professional Science Editing for Scientists @ prosciediting.com