The conservation preference was to restore castles so as to produce what Oliver Creighton and Robert Higham have described as a "meticulously cared for fabric, neat lawns and [a] highly regulated, visitor-friendly environment", although the reconstruction or reproduction of the original appearance of castles was discouraged.
(C, D, E ) Conservation of dinucleotide preferences of the indicated orthologous proteins from fruit fly and human.
In contrast, the preservation of structure at the 3′-end of the helix explains the conservation of nucleotide preferences at adjacent sites of the binding motif.
We compare adoption of conservation practices, and preferences for conservation information sources and communication channels, between farmers who rent some portion of the land they farm (tenants and part-owners) and farmers who own all of the land they farm (full-owners).
DOI: http://dx.doi.org/10.7554/eLife.04837.028 To detect more subtle drift in TF specificity, we analyzed conservation of dinucleotide preferences resulting from structure-based TF-DNA recognition (Rohs et al., 2010; Jolma et al., 2013).
As our analysis is controlled for sequence conservation, the positional preference of structural conservation is not an artifact of the positional preference of sequence conservation.
And yet, the things that President Carter stood for — energy conservation, and the preference for diplomacy over force in the Middle East — somehow don't seem as risible as they did in, say, 1980.
In the −1 and +1 positions both logos show strong conservation and marked preference for threonine.
At position +2 there is a lower level conservation and slight preference for a negative charge (Glu, Asp) in both sets.
The evolutionary conservation, 3'-positional preference and non-random chromosomal distribution all indicate that minimal introns may have special biological functions.
